What to see in Ecuador? If you like sightseeing, you will have plenty to do in Ecuador. First of all, check out the capital city, which is Quito . The city has not only a lot of monuments and attractions (including the largest and best-preserved old town in South America), but above all an extraordinary location. Because Quito is the second, highest-located capital in the world. Santo Domingo and Guayaquil are also noteworthy.